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Ascendis Pharma A/S ASND

11 fiscal years on record · EUR · FY2025 reported · SEC filings only
€720.1M
▲ 98.0% YoY
€-228.0M

Slide the table for earlier years · "·" marks a figure not available in our data for that year.

In brief

What this company does

Ascendis Pharma A/S has two marketed products and four product candidates in clinical development in the Endocrinology Rare Disease and Oncology areas. It does not maintain the capability to manufacture finished drug products and instead uses contract manufacturers to manufacture finished drug product of its TransCon products and product candidates intended for commercial or clinical use. YORVIPATH (palopegteriparatide) has been approved by the U.S. Food and Drug Administration and authorized by the European Commission and other regulatory agencies for the treatment of adults with hypoparathyroidism. Through December 31, 2025, more than 5,300 unique patients had been prescribed YORVIPATH by nearly 2,400 prescribing healthcare providers in the U.S. SKYTROFA (lonapegsomatropin-tcgd) has been approved by the FDA for the treatment of pediatric patients at least one year old who weigh at least 11.5 kg and have growth hormone deficiency, and for growth hormone replacement in adults with the condition. In the United States, SKYTROFA has been commercially available for prescription since October 2021.

Written from the business description in Ascendis Pharma A/S's annual report to the U.S. Securities and Exchange Commission, filed 11 February 2026. Every sentence was checked against that document before publication.

Growth

EUR 720.1M
Revenue, FY2025 · full 11-year series below
Revenue €M Net income €M
FY2025 · Revenue 720.1 · Net income -228.0
300.0M600.0M-250.0M-500.0M
20152018202120242025
Compound annual growth
+141.4%
+153.0%
+56.6%
3 yrs
5 yrs
10 yrs
15 yrs

Revenue compounded at +153.0% a year over the five years to FY2025.

Compound annual rates per period — left blank where that exact year isn't on file, the series crosses a loss, or (per-share rows) a split falls inside the window.

Profitability

−32 cents
lost on every revenue dollar
Operating margin Net margin
FY2025 · Operating -18.9% · Net -31.7%
-2000%-4000%-6000%
201520202025
ROE
FY2022 · ROE -101.7%
-50%-100%
201520202025
Three returns, three denominators.
Return on equityNot applicable: equity was zero or negative in this period, so return on equity has no meaning.

Return on equity has no reading this year — return on capital employed, just below, still does: -54%.

Cash & shareholders

EUR 17.4M
returned in FY2025 · dividends + net buybacks
Free cash flow €M
FY2023 · FCF -469.8
-200M-400M
201520202025
Net buybacks €M Dividends €M
FY2025 · Dividends · · Net buybacks 17.4
50M100M
20212022202320242025

EUR 17.4M in buybacks went back to shareholders in a year without profit.

Total assetsEUR 1.3B
CashEUR 616.0M
Gross debtEUR 720.3M
Net debtEUR 104.2M
Current ratio1.04×

Equity was zero or negative — liabilities equaled or exceeded assets. No ratio is shown.

The 11-year record

11 fiscal years
Every figure from documents filed with the SEC · EUR
row low → row highnegative—not applicable◌not available in our data
ASND, 11-year financial record
Metric 20252024202320222021202020192018201720162015
Revenue €B0.70.40.30.10.00.00.00.00.00.00.0
Operating income €B−0.1−0.3−0.5−0.6−0.5−0.3−0.2−0.2−0.1−0.1−0.0
EBITDA €B◌◌◌◌◌◌◌◌◌◌◌
Income tax €B0.00.00.00.0−0.0−0.0−0.0−0.0−0.0−0.0−0.0
Net income €B−0.2−0.4−0.5−0.6−0.4−0.4−0.2−0.1−0.1−0.1−0.0
Free cash flow €B◌◌−0.5−0.5−0.4−0.3−0.2−0.1−0.1−0.1−0.0
EPS, diluted €−3.76−6.53−8.55−10.40−7.00◌◌◌−3.68−2.58−1.39
Dividend / sh €◌◌◌◌◌◌◌◌◌◌◌
Payout % — not applicable: no dividend———————————
ROE %———−101.7−44.5−58.4−49.7−55.7−68.1−46.1−27.4

Slide the table for earlier years. "—" not applicable · "◌" not available in our data.

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Provenance

Company facts, as filed

How we verify · 0 failures in 46 reconciliationsAUDITED

Reconciled in 11 of the 11 fiscal years we could check. 18 checks were skipped: the balance sheet is not tagged before 2016. 12 checks were skipped: cost of revenue is not tagged before 2019. Eight checks were skipped: EPS is not tagged before 2015.

EPS recomputationBalance-sheet identityGross profitBalance-sheet liquidityCurrency consistency0 failures
ActivityPharmaceutical Preparations
Listed onNASDAQ
Incorporated inoutside the United States — SEC code G7
Fiscal year endsDecember 31
Data on record since2015

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