Karyopharm Therapeutics Inc. KPTI
What this company does
Written from the business description in Karyopharm Therapeutics Inc.'s annual report to the U.S. Securities and Exchange Commission, filed 13 February 2026. Every sentence was checked against that document before publication.
Revenue compounded at +6.2% a year over five years.
Compound annual rates per period — left blank where that exact year isn't on file, the series crosses a loss, or (per-share rows) a split falls inside the window.
EPS, diluted, dividend per share and shares outstanding are shown without shading, and a vertical line marks the year the share count changed — the series crosses a large, unexplained change in share count, so the years on either side are not on a comparable scale.
| Metric | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue $B | 0.1 | 0.1 | 0.1 | 0.2 | 0.2 | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | · | · |
| Operating income $B | −0.1 | −0.1 | −0.1 | −0.1 | −0.1 | −0.2 | −0.2 | −0.2 | −0.1 | −0.1 | −0.1 | −0.1 | −0.0 | −0.0 | −0.0 | · | · |
| EBITDA $B | −0.1 | −0.1 | −0.1 | −0.1 | −0.1 | −0.2 | −0.2 | −0.2 | · | · | · | · | −0.0 | −0.0 | −0.0 | · | · |
| Income tax $B | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | −0.1 | −0.1 | −0.0 | −0.0 | · | · | · |
| Net income $B | −0.2 | −0.1 | −0.1 | −0.2 | −0.1 | −0.2 | −0.2 | −0.2 | −0.1 | −0.1 | −0.1 | −0.1 | −0.0 | −0.0 | −0.0 | −0.0 | −0.0 |
| Free cash flow $B | −0.1 | −0.1 | −0.1 | −0.1 | −0.1 | −0.2 | −0.2 | −0.2 | −0.1 | −0.1 | −0.1 | −0.1 | −0.0 | −0.0 | −0.0 | · | · |
| EPS, diluted $ | −17.93 | −14.00 | −18.79 | −2.02 | −1.65 | −2.72 | −3.22 | −3.14 | −2.81 | −2.92 | −3.32 | −2.43 | −5.59 | −8.95 | −10.27 | · | · |
| Dividend / sh $ | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · |
| Payout % | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · |
| ROE % | · | · | · | · | · | −391.3 | −171.4 | −114.1 | −88.4 | −60.8 | −58.3 | −41.9 | −53.4 | · | · | · | · |
| Shares out B | 0.02 | 0.01 | 0.11 | 0.11 | 0.08 | 0.07 | 0.07 | 0.06 | 0.05 | 0.04 | 0.04 | 0.03 | 0.03 | 0.00 | · | · | · |
Slide the table for earlier years · "·" marks a figure not available in our data for that year.
Reconciled in 17 of 19 fiscal years. 16 checks could not be computed.