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MARKETS / NASDAQ / LXRX
NASDAQ · PHARMACEUTICAL PREPARATIONS · SMALL CAP

Lexicon Pharmaceuticals, Inc. LXRX

17 fiscal years on record · USD · FY2025 reported · SEC filings only
$49.8M
▲ 60.2% YoY
$-50.3M
$-67.9M
In brief

What this company does

It is developing pilavapadin, an orally-delivered small molecule drug candidate, as a treatment for neuropathic pain, and has completed two Phase 2 clinical trials evaluating its safety and tolerability and its effects on diabetic peripheral neuropathic pain. The company was incorporated in Delaware in July 1995, commenced operations in September 1995 and was listed on The Nasdaq Capital Market in April 2000; its corporate headquarters are located at 2445 Technology Forest Blvd., 11th Floor, The Woodlands, Texas 77381. It has developed LX9851, an orally-delivered small molecule drug candidate, as a treatment for obesity and associated cardiometabolic disorders, and has granted Novo Nordisk an exclusive, worldwide, royalty-bearing license to develop, manufacture and commercialize LX9851. As of March 2, 2026, the company employed 81 persons, of whom 15 hold M.D. or Ph.D. degrees and another 22 hold other advanced degrees, and all of its employees are located in the United States.

Written from the business description in Lexicon Pharmaceuticals, Inc.'s annual report to the U.S. Securities and Exchange Commission, filed 5 March 2026. Every sentence was checked against that document before publication.

Growth
USD 49.8M
Revenue, FY2025 · full 17-year series below
Revenue $M Net income $M
FY2025 · Revenue 49.8 · Net income -50.3
50M100M-80M-160M200920112013201520172019202120232025
Compound annual growth
+16.3%
−9.1%
+16.7%
+13.0%
3 yrs
5 yrs
10 yrs
15 yrs

Revenue compounded at +16.3% a year over five years.

Compound annual rates per period — left blank where that exact year isn't on file, the series crosses a loss, or (per-share rows) a split falls inside the window.

Profitability
−101 cents
lost on every revenue dollar
Operating margin Net margin
FY2025 · Operating -98.2% · Net -101.1%
-5000%-10000%200920112013201520172019202120232025
ROE
FY2025 · ROE -39.7%
100%200%-200%-400%200920112013201520172019202120232025

Each USD of equity lost 40 cents this year.

Cash & shareholders
returned in FY2025 · dividends + net buybacks
Free cash flow $M
FY2025 · FCF -67.9
80M160M-80M-160M200920112013201520172019202120232025
Net buybacks $M Dividends $M
FY2024 · Dividends — · Net buybacks 1.7
-80M-160M200920112013201520172019202120232024

Total assetsUSD 185.0M
EquityUSD 107.5M
CashUSD 34.3M
Gross debtUSD 54.0M
Net debtUSD 19.7M
Current ratio4.88×

Net debt stands at 18% of equity.

The 17-year record
17 fiscal years
Every figure from documents filed with the SEC · USD

EPS, diluted, dividend per share and shares outstanding are shown without shading, and a vertical line marks the year the share count changed — the series crosses a large, unexplained change in share count, so the years on either side are not on a comparable scale.

row low → row highnegative
Metric 20252024202320222021202020192018201720162015201420132012201120102009
Revenue $B0.00.00.00.00.00.00.00.00.00.00.10.00.00.00.00.00.0
Operating income $B−0.0−0.2−0.2−0.1−0.1−0.00.1−0.1−0.1−0.10.0−0.1−0.1−0.1−0.1−0.1−0.1
EBITDA $B−0.0−0.2−0.2−0.1−0.1−0.00.1−0.1−0.1−0.10.0−0.1−0.1−0.1−0.1−0.1−0.1
Income tax $B·0.00.00.00.0····0.00.0−0.00.00.00.0−0.0−0.0
Net income $B−0.1−0.2−0.2−0.1−0.1−0.10.1−0.1−0.1−0.1−0.0−0.1−0.1−0.1−0.1−0.1−0.1
Free cash flow $B−0.1−0.2−0.2−0.1−0.1−0.10.1−0.1−0.2−0.20.2−0.1−0.1−0.1−0.1−0.1−0.1
EPS, diluted $−0.14−0.63−0.80−0.62−0.60−0.531.16−1.14−1.17−1.27−0.05−1.31−1.42−0.23−0.34−0.34−0.57
Dividend / sh $·················
Payout %·················
ROE %−39.7−167.7−168.5−88.4−65.0−42.8287.0−576.0−104.3−58.0−1.6−44.2−47.7−39.1−42.7−41.2·
Shares out B0.370.36···············

Slide the table for earlier years · "·" marks a figure not available in our data for that year.

Provenance
Company facts, as filed
How we verify · 0 failures · 1 divergences in 65 reconciliationsAUDITED

Reconciled in 16 of 19 fiscal years. 1 of those reconciliations are divergences — the figures exist but don't fit the formula this check expects; that isn't the same as an error. 19 checks could not be computed.

EPS recomputationBalance-sheet identityGross profitBalance-sheet liquiditymoeda_consistente0 failures1 divergent
ActivityPharmaceutical Preparations
Listed onNASDAQ
Incorporated inDelaware
Fiscal year endsDecember 31
SEC categorysmaller reporting company
Data on record since2009

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