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MARKETS / NASDAQ / MDGL
NASDAQ · PHARMACEUTICAL PREPARATIONS · LARGE CAP

Madrigal Pharmaceuticals, Inc. MDGL

17 fiscal years on record · USD · FY2025 reported · SEC filings only
$958.4M
▲ 432.1% YoY
$-288.3M
$-190.0M
In brief

What this company does

The company does not own or operate, and has no plans to establish, any manufacturing facilities, relying instead on third-party contract manufacturers for starting materials, active pharmaceutical ingredients and finished product, including commercial quantities of Rezdiffra. As of December 31, 2025, it had 915 full-time employees, including 258 engaged in research, development and medical affairs, 526 in commercial activities and 131 in general and administrative functions. Madrigal Pharmaceuticals, Inc. was incorporated in Delaware in March 2000, and its principal executive offices are located at 200 Barr Harbor Drive, Suite 200, West Conshohocken, PA 19428.

Written from the business description in MADRIGAL PHARMACEUTICALS, INC.'s annual report to the U.S. Securities and Exchange Commission, filed 19 February 2026. Every sentence was checked against that document before publication.

Growth
USD 958.4M
Revenue, FY2025 · full 17-year series below
Revenue $M Net income $M
FY2025 · Revenue 958.4 · Net income -288.3
400M800M-200M-400M200920112013201520172019202120232025
Compound annual growth
3 yrs
5 yrs
10 yrs
15 yrs

Compound annual rates per period — left blank where that exact year isn't on file, the series crosses a loss, or (per-share rows) a split falls inside the window.

Profitability
−30 cents
lost on every revenue dollar
Operating margin Net margin
FY2025 · Operating -31.3% · Net -30.1%
-20000%-40000%200920112013201520172019202120232025
ROE
FY2025 · ROE -42.5%
100%200%300%-1000%-2000%200920112013201520172019202120232025

Each USD of equity lost 42 cents this year.

Cash & shareholders
returned in FY2025 · dividends + net buybacks
Free cash flow $M
FY2025 · FCF -190.0
-200M-400M200920112013201520172019202120232025
Net buybacks $M Dividends $M
FY2012 · Dividends — · Net buybacks -66.2
-25.0M-50.0M2012

Total assetsUSD 1.3B
EquityUSD 602.7M
CashUSD 198.7M
Gross debtUSD 339.9M
Net debtUSD 141.2M
Current ratio4.01×

Net debt stands at 23% of equity.

The 17-year record
17 fiscal years
Every figure from documents filed with the SEC · USD

EPS, diluted, dividend per share and shares outstanding are shown without shading, and a vertical line marks the year the share count changed — the series crosses a large, unexplained change in share count, so the years on either side are not on a comparable scale.

row low → row highnegative
Metric 20252024202320222021202020192018201720162015201420132012201120102009
Revenue $B1.00.20.00.00.00.00.00.00.0····0.0···
Operating income $B−0.3−0.5−0.4−0.3−0.2−0.2−0.1−0.0−0.0−0.0−0.0−0.1−0.1−0.1−0.0−0.00.1
EBITDA $B−0.3−0.5−0.4−0.3−0.2−0.2−0.1−0.0−0.0−0.0−0.0−0.1−0.1−0.1−0.0−0.00.1
Income tax $B0.00.00.00.00.00.00.00.0·········
Net income $B−0.3−0.5−0.4−0.3−0.2−0.2−0.1−0.0−0.0−0.0−0.0−0.1−0.1−0.1−0.0−0.00.1
Free cash flow $B−0.2−0.5−0.3−0.2−0.2−0.2−0.0−0.0−0.0−0.0−0.0−0.1−0.1−0.1−0.0−0.0−0.0
EPS, diluted $−12.85−21.90−19.99−17.23−14.63−13.09−5.45−2.22−2.54−5.07−40.03−0.87−1.27−1.06−1.00−0.932.32
Dividend / sh $·················
Payout %·················
ROE %−42.5−80.3−124.0−150.1−110.9−61.6−18.8−10.0−28.5··−2453.9−145.3−139.8−247.7−154.9317.5
Shares out B0.020.020.020.020.020.020.020.020.010.010.000.110.090.070.050.04·

Slide the table for earlier years · "·" marks a figure not available in our data for that year.

Provenance
Company facts, as filed
How we verify · 0 failures in 66 reconciliationsAUDITED

Reconciled in 17 of 19 fiscal years. 26 checks could not be computed.

EPS recomputationBalance-sheet identityGross profitBalance-sheet liquiditymoeda_consistente0 failures
ActivityPharmaceutical Preparations
Listed onNASDAQ
Incorporated inDelaware
Fiscal year endsDecember 31
Data on record since2009

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