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MARKETS / NASDAQ / PRTA
NASDAQ · PHARMACEUTICAL PREPARATIONS · MID CAP

Prothena Corp. Public Ltd. Co. PRTA

15 fiscal years on record · USD · FY2025 reported · SEC filings only
$9.7M
▼ 92.8% YoY
$-244.1M
In brief

What this company does

The Company's ordinary shares began trading on The Nasdaq Global Market under the symbol “PRTA” on December 21, 2012, and currently trade on The Nasdaq Global Select Market. Our goal is to be a leading biotechnology company focused on the discovery and development of novel therapies to treat diseases caused by protein dysregulation. Prothena is developing and applying its proprietary CYTOPE® technology to target a broad spectrum of intracellular disease pathways in the brain and periphery.

Written from the business description in Prothena Corporation plc's annual report to the U.S. Securities and Exchange Commission, filed 27 February 2026. Every sentence was checked against that document before publication.

Growth
USD 9.7M
Revenue, FY2025 · full 15-year series below
Revenue $M Net income $M
FY2025 · Revenue 9.7 · Net income -244.1
80M160M-100M-200M20112013201520172019202120232025
Compound annual growth
−43.6%
+62.6%
+19.7%
3 yrs
5 yrs
10 yrs
15 yrs

Revenue compounded at +62.6% a year over five years.

Compound annual rates per period — left blank where that exact year isn't on file, the series crosses a loss, or (per-share rows) a split falls inside the window.

Profitability
−2521 cents
lost on every revenue dollar
Operating margin Net margin
FY2025 · Operating -2216.4% · Net -2520.6%
-5000%-10000%-15000%20112013201520172019202120232025
ROE
FY2025 · ROE -63.6%
10%20%-20%-40%-60%20112013201520172019202120232025

Each USD of equity lost 64 cents this year.

Cash & shareholders
returned in FY2025 · dividends + net buybacks

Total assetsUSD 326.8M
EquityUSD 280.5M
CashUSD 307.5M
Current ratio7.72×

Equity funds 86% of total assets.

The 15-year record
15 fiscal years
Every figure from documents filed with the SEC · USD
row low → row highnegative
Metric 202520242023202220212020201920182017201620152014201320122011
Revenue $B0.00.10.10.10.20.00.00.00.00.00.00.10.00.0·
Operating income $B−0.2−0.2−0.2−0.10.1−0.1−0.1−0.2−0.2−0.2−0.1−0.0−0.0−0.0−0.0
EBITDA $B−0.2−0.2−0.2−0.10.1−0.1−0.1−0.2−0.2−0.2−0.1−0.0−0.0−0.0−0.0
Income tax $B0.0−0.0−0.0−0.00.0−0.00.0−0.0−0.00.00.00.00.00.00.0
Net income $B−0.2−0.1−0.1−0.10.1−0.1−0.1−0.2−0.2−0.2−0.1−0.0−0.0−0.0−0.0
EPS, diluted $−4.53−2.27−2.76−2.471.38−2.78−1.95−3.93−4.07−4.66−2.66−0.29−2.20−2.84−2.05
Dividend / sh $···············
Payout %···············
ROE %−63.6−23.3−24.8−21.520.6−48.6−26.1−42.6−39.7−44.1−24.8−3.1−27.4−32.7·
Shares out B0.050.050.050.050.050.040.040.040.040.030.030.030.020.02·

Slide the table for earlier years · "·" marks a figure not available in our data for that year.

Provenance
Company facts, as filed
How we verify · 0 failures in 58 reconciliationsAUDITED

Reconciled in 15 of 19 fiscal years. 18 checks could not be computed.

EPS recomputationBalance-sheet identityGross profitBalance-sheet liquiditymoeda_consistente0 failures
ActivityPharmaceutical Preparations
Listed onNASDAQ
Incorporated inoutside the United States — SEC code L2
Fiscal year endsDecember 31
Data on record since2011

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