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MARKETS / NYSE / SER
NYSE · PHARMACEUTICAL PREPARATIONS · SMALL CAP

Serina Therapeutics, Inc. SER

9 fiscal years on record · USD · FY2025 reported · SEC filings only
$130,000
▲ 132.1% YoY
$-19.2M
$-18.0M
In brief

What this company does

We are a clinical-stage biotechnology company developing a pipeline of wholly-owned drug product candidates to treat neurological diseases and other indications. Our POZ drug delivery technology is designed to enable certain existing drugs and novel drug candidates to be modified in a way that provides the potential to improve the integrated efficacy and safety profile of multiple modalities including small molecules, RNA-based therapeutics and antibody-based drug conjugates (ADCs). The Company’s proprietary POZ technology is based on a synthetic, water soluble, low viscosity polymer called poly(2-oxazoline) and is engineered to provide greater control in drug loading and more precision in the rate of release of attached drugs delivered via easy-to-administer, long-acting subcutaneous injection. Our lead product candidate, SER 252 (POZ-apomorphine), is a POZ conjugate of the potent dopamine agonist apomorphine being developed for the treatment of Parkinson’s disease and is in clinical development. SER 252 is designed to provide CDS via a subcutaneous injection delivered one to two times per week. We believe that our POZ platform delivery technology has potential for use across a broad range of payloads and indications.

Written from the business description in Serina Therapeutics, Inc.'s annual report to the U.S. Securities and Exchange Commission, filed 25 March 2026. Every sentence was checked against that document before publication.

Growth
USD 130,000.00
Revenue, FY2025 · full 9-year series below
Revenue $M Net income $M
FY2025 · Revenue 0.1 · Net income -19.2
2M4M-8M-16M201720182019202020212022202320242025
Compound annual growth
+56.4%
−18.5%
3 yrs
5 yrs
10 yrs
15 yrs

Revenue compounded at −18.5% a year over five years.

Compound annual rates per period — left blank where that exact year isn't on file, the series crosses a loss, or (per-share rows) a split falls inside the window.

Profitability
−14781 cents
lost on every revenue dollar
Operating margin Net margin
FY2025 · Operating -18478.5% · Net -14780.8%
-10000%-20000%-30000%201720182019202020212022202320242025
ROE
FY2025 · ROE -6351.7%
-2000%-4000%-6000%201720182019202020212022202320242025

Each USD of equity lost 6352 cents this year.

Cash & shareholders
returned in FY2025 · dividends + net buybacks
Free cash flow $M
FY2025 · FCF -18.0
-8M-16M201720182019202020212022202320242025

Total assetsUSD 7.0M
EquityUSD -37,000.00
CashUSD 3.1M
Current ratio1.71×

Equity funds -1% of total assets.

The 9-year record
9 fiscal years
Every figure from documents filed with the SEC · USD

EPS, diluted, dividend per share and shares outstanding are shown without shading, and a vertical line marks the year the share count changed — the series crosses a large, unexplained change in share count, so the years on either side are not on a comparable scale.

row low → row highnegative
Metric 202520242023202220212020201920182017
Revenue $B0.00.00.00.00.00.00.00.00.0
Operating income $B−0.0−0.0−0.0−0.0−0.0−0.0−0.0−0.0−0.0
EBITDA $B−0.0−0.0···−0.0−0.0−0.0−0.0
Income tax $B0.00.00.0··−0.00.0··
Net income $B−0.0−0.00.0−0.0−0.0−0.0−0.0−0.0−0.0
Free cash flow $B−0.0−0.0−0.0··−0.0−0.0−0.0−0.0
EPS, diluted $−1.91−1.510.73−9.70−0.23−0.29−0.33−0.21−0.21
Dividend / sh $·········
Payout %·········
ROE %−6351.7·····−251.5−101.9−90.4
Shares out B0.010.010.000.000.040.040.040.040.03

Slide the table for earlier years · "·" marks a figure not available in our data for that year.

Provenance
Company facts, as filed
How we verify · 0 failures in 43 reconciliationsAUDITED

Reconciled in 9 of 19 fiscal years. 52 checks could not be computed.

EPS recomputationBalance-sheet identityGross profitBalance-sheet liquiditymoeda_consistente0 failures
ActivityPharmaceutical Preparations
Listed onNYSE
Incorporated inAlabama
Fiscal year endsDecember 31
SEC categorysmaller reporting company
Data on record since2017

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