MARKETS / NASDAQ / SYRE
NASDAQ · PHARMACEUTICAL PREPARATIONS · LARGE CAP

Spyre Therapeutics, Inc. SYRE

12 fiscal years on record · USD · FY2025 reported
SEC FILINGS ONLY
EPS · FY25
Dividend / sh · FY25
Payout · FY25
ROE · FY25
-25.2%
Net margin · FY25
Dividend coverage
Advertisement
AdSense · Leaderboard 728×90320×100
Result
Revenue, FY2025 · full 12-year series below
Revenue Net income
0.0050.010.0150.020.0-0.220142017202020232025
0.0050.010.0150.020.0-0.22016201920222025

Per share
Diluted EPS, FY2025
EPS
0.40.81.220142017202020232025
0.40.81.22016201920222025

The company pays no cash dividend.

Profitability
-25.2%
Return on equity, FY2025
ROE
0.250.50.751-25.2%20142017202020232025
0.250.50.751-25.2%2016201920222025
Operating margin
Net margin
Return on assets-22.4%

Each USD of equity lost 25 cents this year.

Returned to shareholders
returned in FY2025 · dividends + net buybacks
Dividends paid
Net buybacks
Share of profit
Consecutive raises

Growth
revenue, compounded over five years
CAGR
3 yrs
5 yrs
10 yrs
15 yrs

Compound annual rates per period — left blank where the series crosses a loss.

Share base
Shares outstanding, FY2025
Change, 5 years
Change, 10 years

A share split breaks the comparison across the period, so we leave it out.

Advertisement
AdSense · Leaderboard 728×90300×250
Balance sheet
USD 777.8M
total assets, end of FY2025
Total assetsUSD 777.8M
EquityUSD 715.2M
CashUSD 85.7M
Current ratio13.25×

Equity funds 92% of total assets.

History
12 fiscal years
Every figure from documents filed with the SEC · USD
Metric
2025
2024
2023
2022
2021
2020
2019
2018
2017
2016
2015
2014
Revenue $B
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
·
·
Operating income $B
−0.2
−0.2
−0.2
−0.1
−0.1
−0.1
−0.1
−0.0
−0.0
−0.0
−0.0
−0.0
EBITDA $B
−0.2
−0.2
−0.2
−0.1
−0.1
−0.1
−0.1
−0.0
−0.0
−0.0
−0.0
−0.0
Income tax $B
−0.0
0.0
−0.0
−0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
Net income $B
−0.2
−0.2
−0.3
−0.1
−0.1
−0.1
−0.1
−0.0
−0.0
−0.0
−0.0
−0.0
EPS, diluted $
·
·
·
·
·
·
·
·
·
·
·
·
Dividend / sh $
·
·
·
·
·
·
·
·
·
·
·
·
Payout %
·
·
·
·
·
·
·
·
·
·
·
·
ROE %
−25.2
−59.3
−289.2
−124.9
−58.8
−80.9
−122.7
−75.3
−48.1
−106.5
·
·
Shares out B
·
·
·
·
·
·
·
·
·
·
·
·

Slide the table for earlier years · "·" marks figures not disclosed in the filing for that year.

How we verifyAUDITED
31 of 31
checks passed before publication
EPS recomputationBalance-sheet identityGross profitBalance-sheet liquidity

Every figure was compared against the original statement: 0 failures and 0 presentation gaps.

What we don’t show

We’d rather say what’s missing than fill the gap with an estimate.

P/E rationeeds a market quote — not yet licensed
Market capitalizationneeds a market quote — not yet licensed
Dividend yieldneeds a market quote — not yet licensed
Price-to-bookneeds a market quote — not yet licensed