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NASDAQ · PHARMACEUTICAL PREPARATIONS · LARGE CAP

Vertex Pharmaceuticals Inc. VRTX

18 fiscal years on record · USD · FY2025 reported · SEC filings only
$12.0B
▲ 8.9% YoY
$4.0B
$3.2B

Slide the table for earlier years · "·" marks a figure not available in our data for that year.

In brief

What this company does

The company markets and sells its approved products and advances product candidates through clinical development toward commercialization. The company's marketed cystic fibrosis medicines, including ALYFTREK, TRIKAFTA/KAFTRIO, SYMDEKO/SYMKEVI, ORKAMBI, and KALYDECO, reach nearly three quarters of the approximately 97,000 people with cystic fibrosis in the U.S., Europe, Australia, and Canada. Its cystic fibrosis medicines are reimbursed or accessible in more than 60 countries across six continents. JOURNAVX was approved by the U.S. Food and Drug Administration in January 2025 for the treatment of moderate-to-severe acute pain in adults. The company has established its own small molecule manufacturing capabilities in Boston, which it uses for clinical trial and commercial supplies, including certain manufacturing steps for its commercial supply of TRIKAFTA/KAFTRIO. As of December 31, 2025, the company had approximately 6,400 employees.

Written from the business description in VERTEX PHARMACEUTICALS INC / MA's annual report to the U.S. Securities and Exchange Commission, filed 13 February 2026. Every sentence was checked against that document before publication.

Growth

USD 12.0B
Revenue, FY2025 · full 18-year series below
Revenue $B Net income $B
FY2025 · Revenue 12.0 · Net income 4.0
5B10B
2008201120142017202020232025
Compound annual growth
+10.4%
+14.1%
+27.8%
+34.3%
+6.0%
+7.8%
+6.1%
+8.3%
3 yrs
5 yrs
10 yrs
15 yrs

Revenue compounded at +14.1% a year over the five years to FY2025 — but profit grew slower: net income at +7.8%, earnings per share at +8.3%.

The share count fell from 0.26B to 0.25B — the buyback concentrates the same profit into fewer slices.

Compound annual rates per period — left blank where that exact year isn't on file, the series crosses a loss, or (per-share rows) a split falls inside the window.

Profitability

33 cents
of every revenue dollar became profit
Operating margin Net margin
FY2025 · Operating 34.8% · Net 32.9%
-200%-400%-600%
200820162025
ROE
FY2025 · ROE 22.5%
20%40%60%-50%
200820162025
Three returns, three denominators.

Each USD of equity produced 23 cents of profit this year.

Cash & shareholders

USD 2.0B
returned in FY2025 · dividends + net buybacks
Free cash flow $B
FY2025 · FCF 3.2
1.5B3.0B-0.3B-0.6B
200820162025
Net buybacks $B Dividends $B
FY2025 · Dividends · · Net buybacks 2.0
1.0B2.0B-0.1B-0.3B
2016201720182019202020212022202320242025

USD 2.0B in buybacks — 50% of the year's profit went back to shareholders.

Total assetsUSD 25.6B
EquityUSD 18.7B
CashUSD 5.1B
Current ratio2.90×

Equity funds 73% of total assets.

The 18-year record

18 fiscal years
Every figure from documents filed with the SEC · USD
row low → row highnegative—not applicable◌not available in our data
VRTX, 18-year financial record
Metric 202520242023202220212020201920182017201620152014201320122011201020092008
Revenue $B12.011.09.98.97.66.24.23.02.51.71.00.61.21.51.40.10.10.2
Operating income $B4.2−0.23.84.32.82.91.20.60.10.0−0.5−0.7−0.60.00.1−0.7−0.6−0.5
EBITDA $B4.4−0.04.04.52.93.01.30.70.20.1−0.4−0.6−0.60.10.1−0.7−0.6−0.4
Income tax $B0.70.80.80.90.40.40.2−1.5−0.10.00.00.0−0.1−0.00.00.0◌◌
Net income $B4.0−0.53.63.32.32.71.22.10.3−0.1−0.6−0.7−0.4−0.10.0−0.8−0.6−0.5
Free cash flow $B3.2−0.83.33.92.43.01.51.20.70.2−0.4−0.6−0.10.20.1−0.7−0.5−0.3
EPS, diluted $15.32−2.0813.8912.829.0110.294.518.091.04−0.46−2.31−3.14−1.98−0.500.14−3.77−3.71−3.27
Dividend / sh $◌◌◌◌◌◌◌◌◌◌◌◌◌◌◌◌◌◌
Payout % — not applicable: no dividend——————————————————
ROE %22.5−3.223.027.724.936.722.464.916.5−10.7−55.2−60.8−37.8−12.04.6−94.3−96.2◌
Shares out B0.250.260.260.260.250.260.260.260.250.250.250.240.230.220.210.200.20◌

Slide the table for earlier years. "—" not applicable · "◌" not available in our data.

More in this sector

Other companies filing in the same sector

Provenance

Company facts, as filed

How we verify · 0 failures in 70 reconciliationsAUDITED

Reconciled in 18 of the 18 fiscal years we could check. Four checks were skipped: the balance sheet is not tagged before 2009. Three checks were skipped: cost of revenue is not tagged before 2010. One check was skipped: EPS is not tagged before 2008.

EPS recomputationBalance-sheet identityGross profitBalance-sheet liquidityCurrency consistency0 failures
ActivityPharmaceutical Preparations
Listed onNASDAQ
Incorporated inMassachusetts
Fiscal year endsDecember 31
Data on record since2008

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