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MARKETS / NASDAQ / CRBU
NASDAQ · BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES) · SMALL CAP

Caribou Biosciences, Inc. CRBU

7 fiscal years on record · USD · FY2025 reported · SEC filings only
$11.2M
▲ 11.7% YoY
$-148.1M
$-112.4M
In brief

What this company does

We use our chRDNA technology to armor our cell therapy product candidates through genome-editing strategies, such as checkpoint disruption and immune cloaking, to enhance activity against hematologic malignancies. On April 24, 2025, we announced a strategic pipeline prioritization with workforce and cost reduction initiatives to focus resources on our vispa-cel and CB-011 product candidates. As of February 27, 2026, we owned 27 trademark registrations worldwide, including 7 U.S. trademark registrations. We have registered “CARIBOU,” “CARIBOU BIOSCIENCES,” “SITE-SEQ,” and the Caribou logo as trademarks in relevant classes in the United States, European Union (“EU”), and certain other jurisdictions. As of February 27, 2026, we had 97 total employees, all of whom were full-time. The majority of our employees are located in Berkeley, California.

Written from the business description in Caribou Biosciences, Inc.'s annual report to the U.S. Securities and Exchange Commission, filed 5 March 2026. Every sentence was checked against that document before publication.

Growth
USD 11.2M
Revenue, FY2025 · full 7-year series below
Revenue $M Net income $M
FY2025 · Revenue 11.2 · Net income -148.1
20M-50M-100M2019202020212022202320242025
Compound annual growth
−7.0%
−2.0%
3 yrs
5 yrs
10 yrs
15 yrs

Revenue compounded at −2.0% a year over five years.

Compound annual rates per period — left blank where that exact year isn't on file, the series crosses a loss, or (per-share rows) a split falls inside the window.

Profitability
−1327 cents
lost on every revenue dollar
Operating margin Net margin
FY2025 · Operating -1329.4% · Net -1327.4%
-500%-1000%-1500%2019202020212022202320242025
ROE
FY2025 · ROE -79.0%
-100%-200%-300%2019202020212022202320242025

Each USD of equity lost 79 cents this year.

Cash & shareholders
returned in FY2025 · dividends + net buybacks
Free cash flow $M
FY2025 · FCF -112.4
-50M-100M2019202020212022202320242025

Total assetsUSD 175.4M
EquityUSD 122.2M
CashUSD 12.4M
Current ratio5.71×

Equity funds 70% of total assets.

The 7-year record
7 fiscal years
Every figure from documents filed with the SEC · USD

EPS, diluted, dividend per share and shares outstanding are shown without shading, and a vertical line marks the year the share count changed — the series crosses a large, unexplained change in share count, so the years on either side are not on a comparable scale.

row low → row highnegative
Metric 2025202420232022202120202019
Revenue $B0.00.00.00.00.00.00.0
Operating income $B−0.1−0.2−0.1−0.1−0.1−0.0−0.0
EBITDA $B−0.1−0.2−0.1−0.1−0.1−0.0−0.0
Income tax $B−0.0−0.00.00.00.0−0.0−0.0
Net income $B−0.1−0.1−0.1−0.1−0.1−0.0−0.0
Free cash flow $B−0.1−0.1−0.1−0.1−0.0−0.0−0.0
EPS, diluted $−1.59−1.65−1.38−1.64−2.11−4.01−2.80
Dividend / sh $·······
Payout %·······
ROE %−79.0−48.0−30.5−28.9−36.7·−314.0
Shares out B0.100.090.090.060.060.01·

Slide the table for earlier years · "·" marks a figure not available in our data for that year.

Provenance
Company facts, as filed
How we verify · 0 failures in 26 reconciliationsAUDITED

Reconciled in 7 of 19 fiscal years. 50 checks could not be computed.

EPS recomputationBalance-sheet identityGross profitBalance-sheet liquiditymoeda_consistente0 failures
ActivityBiological Products, (No Diagnostic Substances)
Listed onNASDAQ
Incorporated inDelaware
Fiscal year endsDecember 31
SEC categoryemerging growth company, smaller reporting company
Data on record since2019

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