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MARKETS / NASDAQ / GANX
NASDAQ · PHARMACEUTICAL PREPARATIONS · SMALL CAP

Gain Therapeutics, Inc. GANX

6 fiscal years on record · USD · FY2025 reported · SEC filings only
$-20.2M
In brief

What this company does

GT-02287 - our lead product candidate, for the treatment of Parkinson’s disease, is currently being evaluated in a Phase 1b study in people with Parkinson’s disease with or without a GBA1 mutation. We have generated an extensive preclinical data package providing evidence of the mechanism of action and safety of GT-02287. In September 2024, we reported results from a first-in-human Phase 1 clinical trial completed in Australia to assess the safety, tolerability, pharmacokinetics, and food effect of GT-02287 in healthy participants. The study enrolled 72 healthy volunteers and included a single ascending dose part during which study participants (n=40) received one dose of GT-02287 at different dose levels, and a multiple ascending dose part during which study participants (n=32) received one daily dose of GT-02287 for 14 days at different dose levels. The PK profile of GT-02287 was linear across the tested dose ranges, and plasma exposures at daily doses of 7.7 mg/kg and above were within the projected therapeutic range.

Written from the business description in Gain Therapeutics, Inc's annual report to the U.S. Securities and Exchange Commission, filed 26 March 2026. Every sentence was checked against that document before publication.

Growth
Revenue, FY2025 · full 6-year series below
Revenue $M Net income $M
FY2023 · Revenue 0.1 · Net income -22.3
-8M-16M202020212022202320242025
Compound annual growth
+24.1%
3 yrs
5 yrs
10 yrs
15 yrs

Compound annual rates per period — left blank where that exact year isn't on file, the series crosses a loss, or (per-share rows) a split falls inside the window.

Profitability
Operating margin Net margin
FY2023 · Operating -40328.3% · Net -40354.3%
-20000%-40000%202020212022202320242025
ROE
FY2025 · ROE -155.7%
-100%-200%202020212022202320242025

Each USD of equity lost 156 cents this year.

Cash & shareholders
returned in FY2025 · dividends + net buybacks
Free cash flow $M
FY2024 · FCF -18.9
-8M-16M202020212022202320242025

Total assetsUSD 22.8M
EquityUSD 18.6M
CashUSD 20.8M
Gross debtUSD 400,953.00
Net debtUSD -20.4M
Current ratio6.63×

The company holds more cash than debt.

The 6-year record
6 fiscal years
Every figure from documents filed with the SEC · USD

EPS, diluted, dividend per share and shares outstanding are shown without shading, and a vertical line marks the year the share count changed — the series crosses a large, unexplained change in share count, so the years on either side are not on a comparable scale.

row low → row highnegative
Metric 202520242023202220212020
Revenue $B··0.00.00.00.0
Operating income $B−0.0−0.0−0.0−0.0−0.0−0.0
EBITDA $B−0.0−0.0−0.0−0.0−0.0−0.0
Income tax $B0.00.00.00.00.00.0
Net income $B−0.0−0.0−0.0−0.0−0.0−0.0
Free cash flow $B·−0.0−0.0−0.0−0.0−0.0
EPS, diluted $−0.61−0.89−1.71−1.48−1.37−1.33
Dividend / sh $······
Payout %······
ROE %−155.7−205.0−141.6−65.5−67.7−57.7
Shares out B0.040.030.020.010.010.00

Slide the table for earlier years · "·" marks a figure not available in our data for that year.

Provenance
Company facts, as filed
How we verify · 0 failures in 24 reconciliationsAUDITED

Reconciled in 6 of 19 fiscal years. 52 checks could not be computed.

EPS recomputationBalance-sheet identityGross profitBalance-sheet liquiditymoeda_consistente0 failures
ActivityPharmaceutical Preparations
Listed onNASDAQ
Incorporated inDelaware
Fiscal year endsDecember 31
SEC categoryemerging growth company, smaller reporting company
Data on record since2020

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